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| Les deux révisions précédentes Révision précédente Prochaine révision | Révision précédente | ||
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acupuncture:evaluation:stomatologie:03. xerostomie [29 Apr 2020 08:32] Nguyen Johan |
acupuncture:evaluation:stomatologie:03. xerostomie [28 Aug 2025 19:25] (Version actuelle) Nguyen Johan [1.3.3. Sjögren's Syndrome] |
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| + | /*English:Xerostomia*/ | ||
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| + | ======= Xerostomia ======= | ||
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| ====== Xérostomie : évaluation de l'acupuncture ====== | ====== Xérostomie : évaluation de l'acupuncture ====== | ||
| | //Articles connexes//: - [[acupuncture:conduites therapeutiques:stomatologie:03. xerostomie|conduites thérapeutiques]] - pathologie - acupuncture expérimentale - qigong - | | | //Articles connexes//: - [[acupuncture:conduites therapeutiques:stomatologie:03. xerostomie|conduites thérapeutiques]] - pathologie - acupuncture expérimentale - qigong - | | ||
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| ===== Revues systématiques et méta-analyses===== | ===== Revues systématiques et méta-analyses===== | ||
| - | | ☆☆☆ | Preuves en faveur d’une efficacité et d’un effet spécifique de l’acupuncture | | + | | ☆☆☆ | Evidence for effectiveness and a specific effect of acupuncture | |
| - | | ☆☆ | Preuves en faveur d’une efficacité de l’acupuncture | | + | | ☆☆ | Evidence for effectiveness of acupuncture | |
| - | | ☆ |Preuves limitées en faveur d’une efficacité de l’acupuncture | | + | | ☆ |Limited evidence for effectiveness of acupuncture | |
| - | | Ø |Absence de preuve ou preuves insuffisantes | | + | | Ø |No evidence or insufficient evidence | |
| - | ==== Acupuncture générique ==== | + | ==== Generic Acupuncture ==== |
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| ^Results|Thirty-six studies (3,274 patients) were included in the systematic review. Results from the meta-analyses showed high-quality evidence that pilocarpine was superior to placebo in reducing dry mouth symptoms. We found moderate quality of evidence that pilocarpine, rituximab and interferon-alpha were more effective than placebo in increasing salivary flow, with the relevant effect size being large for pilocarpine, and notably smaller for rituximab and interferon-alpha. | | ^Results|Thirty-six studies (3,274 patients) were included in the systematic review. Results from the meta-analyses showed high-quality evidence that pilocarpine was superior to placebo in reducing dry mouth symptoms. We found moderate quality of evidence that pilocarpine, rituximab and interferon-alpha were more effective than placebo in increasing salivary flow, with the relevant effect size being large for pilocarpine, and notably smaller for rituximab and interferon-alpha. | | ||
| ^ Conclusion|Clinicians should be very confident in the beneficial effects of pilocarpine upon dry mouth symptoms of SS and moderately confident that pilocarpine, rituximab and interferon-alpha can have beneficial effects upon salivary flow. Adverse events are common. The use of other treatment modalities cannot be supported on the basis of current evidence. | | ^ Conclusion|Clinicians should be very confident in the beneficial effects of pilocarpine upon dry mouth symptoms of SS and moderately confident that pilocarpine, rituximab and interferon-alpha can have beneficial effects upon salivary flow. Adverse events are common. The use of other treatment modalities cannot be supported on the basis of current evidence. | | ||
| - | | Acupuncture | the present systematic review suggests that there is no evidence that the use of DMARDs, acupuncture, laser acupuncture, infliximab, etanercept and other interventions (gamma‐linolenic acid, dehydroepiandrosterone, omega‐3/vit E, nizatidine, a traditional chinese medicine compound) can reduce symptoms of dry mouth or increase salivary flow in individuals with SS.| | + | | Acupuncture | the present systematic review suggests that there is no evidence that the use of DMARDs, acupuncture, laser acupuncture (2 studies), infliximab, etanercept and other interventions (gamma‐linolenic acid, dehydroepiandrosterone, omega‐3/vit E, nizatidine, a traditional chinese medicine compound) can reduce symptoms of dry mouth or increase salivary flow in individuals with SS.| |
| === Assy 2018 Ø === | === Assy 2018 Ø === | ||
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| - | ==== Formes cliniques particulières ==== | + | ==== Special Clinical Forms ==== |
| - | === Xérostomie des cancers avancés === | + | === Xerostomia in Advanced Cancer Patients. === |
| - | == Hanchanale 2015 ☆ (à l'exclusion des xérostomies post-radiques) == | + | == Hanchanale 2015 ☆ (Radiation-Induced Xerostomia excluded) == |
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| - | === Xérostomie post-radique === | + | === Radiation-Induced Xerostomia in Cancer Patients=== |
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| + | | See [[acupuncture:evaluation:oncologie:03. xerostomie post-radique|corresponding item]] | | ||
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| + | === Sjögren's Syndrome === | ||
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| + | | See [[acupuncture:evaluation:medecine interne. divers:06. syndrome de sjogren|corresponding item]] | | ||
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| - | |Voir l'[[acupuncture:evaluation:oncologie:03. xerostomie post-radique|article correspondant]] | | + | ===== Overviews of systematic reviews ===== |
| - | === Syndrome de Sjögren === | + | == Conte 2025 == |
| + | Conte DB, Marquezzan ME, Schneider LR, Gauer APM, Cattapan L, Corralo VDS, Rodrigues-Junior SA. Systematic Reviews on the Management of Xerostomia and Hyposalivation-An Umbrella Review. Gerodontology. 2025 Jun;42(2):165-176. https://doi.org/10.1111/ger.12809 | ||
| + | ^Introduction| Dry mouth is moderately prevalent in the older population. Pharmacological and non-pharmacological alternatives have been assessed to manage its manifestation. This umbrella review synthesised the evidence on approaches to managing xerostomia and hyposalivation.| | ||
| + | ^Material and methods| We searched for systematic reviews of interventions to manage dry mouth in Cochrane Database of Systematic Reviews, EMBASE, PubMed, Prospero and DARE databases (up to September 2023). References were managed and selected by reading titles and abstracts using Rayyan QCRI. Selection of studies, data extraction and methodological quality assessment (AMSTAR 2) were conducted independently, in duplicate. Data were extracted to a previously tested form that included information about dry mouth causes, interventions, outcomes and findings.| | ||
| + | ^Results| There were 3323 records. At the end of the selection process, 48 studies were included and had data extracted. Only three high-quality systematic reviews were found to support methods for managing dry mouth. Limited evidence suggests that topical therapies offer significant palliative or stimulating effects for relieving dry mouth symptoms. Furthermore, low-quality evidence indicates a slight increase in saliva production with acupuncture, dry mouth prevention with amifostine, and saliva stimulation using pilocarpine in patients who have undergone head and neck radiotherapy.| | ||
| + | ^Conclusion| Salivary substitutes and stimulants mostly acted as moisturisers and some as saliva stimulants, with short-term effect. More than 80% of the reviews were appraised as 'critically low' quality. Well-designed and well-reported systematic reviews are still needed to increase the level of evidence on dry mouth management methods.| | ||
| - | | Voir l' [[acupuncture:evaluation:medecine interne. divers:06. syndrome de sjogren|article correspondant]] | | ||
