Différences
Ci-dessous, les différences entre deux révisions de la page.
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acupuncture:evaluation:oncologie:04. neuropathie peripherique induite par chimiotherapie [28 Aug 2025 19:06] Nguyen Johan [2. Overviews of Systematic Reviews] |
acupuncture:evaluation:oncologie:04. neuropathie peripherique induite par chimiotherapie [24 Oct 2025 18:41] (Version actuelle) Nguyen Johan [1.1.1. Zhao 2025] |
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| ==== Generic Acupuncture ==== | ==== Generic Acupuncture ==== | ||
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| + | === Tian 2025 === | ||
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| + | Tian H, Luo Q, Huang L, Chen G, Sun M, Liang F. Exploration of the quantitative-effectiveness association between acupuncture temporal parameters and chemotherapy-induced peripheral neuropathy in cancer patients: a dose-response meta-analysis of randomized controlled trials. Front Oncol. 2025 Feb 12;14:1527331. https://doi.org/10.3389/fonc.2024.1527331. | ||
| + | ^Backgound| Chemotherapy-induced peripheral neuropathy (CIPN) is one of the commonly reported symptoms impacting cancer survivors. This study evaluated and compared the effectiveness of acupuncture treatments for CIPN.| | ||
| + | ^Methods| We searched six databases from their inception to August 2024 to identify eligible randomized controlled trials (RCTs). Primary outcome were pain scores. Secondary outcomes were quality of life including FACT/GOG-Ntx and EORTC QLQ-C30. The robust error meta-regression (REMR) method was used to evaluate the dose-response relationship across treatment parameters, including number of sessions, frequency, and duration.| | ||
| + | ^Results| In total, **11 RCTs featuring 740 participants** were included. The meta-analysis demonstrated that the primary analysis achieved a significant reduction in pain scores, with a standardized mean difference of [SMD= -1.23, 95% CI = (-2.22, -0.24); P < 0.01; I² = 95%], improvement quality of life including FACT/GOG-Ntx [SMD = 0.95, 95% CI = (0.02, 1.88); P < 0.01; I² = 93%] and EORTC QLQ-C30 [SMD = 0.36, 95% CI = (0.03, 0.68); P = 0.14; I² = 46%]. The nonlinear dose-response analysis suggests that pain improvement achieves the MCID at 16 treatment sessions, over 8 weeks, with a frequency of twice per week. Furthermore, analysis of the treatment duration chart shows that acupuncture maintains therapeutic effects during the follow-up period. Sensitivity analysis confirmed the robustness of these findings.| | ||
| + | ^Conclusion| Acupuncture demonstrates significant potential in managing CIPN, particularly through individualized treatment regimens. The identified time-dose-response relationship suggests that tailoring acupuncture frequency and duration can to optimize pain relief in CIPN patients. Future high-quality studies and large-scale multicenter clinical trials are needed to validate these findings.| | ||
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| === Zhao 2025 === | === Zhao 2025 === | ||
