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acupuncture:evaluation:gyneco-obstetrique:10. nausees et vomissements gravidiques [20 Dec 2020 07:31] Nguyen Johan Les liens vers %s ont été changés vers %s |
acupuncture:evaluation:gyneco-obstetrique:10. nausees et vomissements gravidiques [17 Oct 2025 13:45] (Version actuelle) Nguyen Johan [2. Clinical Practice Guidelines] |
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| /*English:Nausea and Vomiting in Pregnancy*/ | /*English:Nausea and Vomiting in Pregnancy*/ | ||
| - | ====== nausea and vomiting in pregnancy: effectiveness of acupuncture ====== | + | ====== nausea and vomiting in pregnancy: ====== |
| ====== Nausées-vomissements gravidiques : évaluation de l'acupuncture ====== | ====== Nausées-vomissements gravidiques : évaluation de l'acupuncture ====== | ||
| - | | Articles connexes : - [[acupuncture:evaluation:oncologie:04. nausees-vomissements post-chimiotherapie|Nausées et vomissements post-chimiothérapie]] - [[acupuncture:evaluation:soins peri-operatoires:07. nausees et vomissements post-operatoires|Nausées et vomissements post-opératoires]] -| | + | | Articles connexes : - [[acupuncture:evaluation:oncologie:04. nausees et vomissements chimio-induits|Nausées et vomissements post-chimiothérapie]] - [[acupuncture:evaluation:soins peri-operatoires:07. nausees et vomissements post-operatoires|Postoperative Nausea and Vomiting]] |
| ===== Systematic Reviews and Meta-Analysis===== | ===== Systematic Reviews and Meta-Analysis===== | ||
| - | | ☆☆☆ | Evidence for effectiveness and a specific effect of acupuncture | | + | |
| - | | ☆☆ | Evidence for effectiveness of acupuncture | | + | |
| - | | ☆ |Limited evidence for effectiveness of acupuncture | | + | |
| - | | Ø |No evidence or insufficient evidence | | + | |
| ==== Generic Acupuncture ==== | ==== Generic Acupuncture ==== | ||
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| + | === Hu 2024 === | ||
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| + | Hu Y, Yang Q, Hu X. The efficacy and safety of acupuncture and moxibustion for the management of nausea and vomiting in pregnant women: A systematic review and meta-analysis. Heliyon. 2024 Jan 11;10(2):e24439. https://doi.org/10.1016/j.heliyon.2024.e24439 | ||
| + | ^Backgound| Nausea and vomiting, which cause considerable multifaceted effects, are commonly experience in early pregnancy. Various therapeutic strategies are employed, including both conventional agents and complementary medicine. However, the effectiveness of complementary medicine remains controversial. The objective of this meta-analysis is to evaluate efficacy and safety of acupuncture and moxibustion in pregnant women.| | ||
| + | ^Methods| We conducted a comprehensive search using electronic databases such as PubMed, Embase, ISI Web, Medline, Cochrane, clinicaltrial.gov, and several Chinese databases. A total of ** 21 randomized controlled trials** were included in this study for quantitative analysis. Forest plots were utilized to evaluate the efficacy and safety of acupuncture and moxibustion. Egger's test was employed to assess publication bias.| | ||
| + | ^Results| The pooled analysis revealed that the acupuncture/moxibustion group was more effective than control group in alleviating nausea and vomiting in early pregnant women (RR: 0.28; 95%CI: 0.21, 0.37). Similar results were observed when comparing the acupuncture group to traditional herbs (RR: 0.08; 95 % CI: 0.01, 0.60), conventional therapy (RR: 0.15; 95 % CI: 0.04, 0.57), and the blank control group (RR: 0.33; 95 % CI: 0.22, 0.51). Moxibustion also exhibited the ability to alleviate nausea and vomiting compared with the blank control group (RR: 0.21; 95 % CI: 0.08, 0.52). As for safety, there were no significant differences in severe adverse events between the acupuncture group and the control group (RR: 0.77; 95%CI: 0.52, 1.14), the blank control group (RR: 0.61; 95%CI: 0.34, 1.10), the sham acupuncture group (RR: 1.05; 95%CI: 0.63, 1.73), or the conventional therapy group (RR: 0.32; 95%CI: 0.06, 1.55).| | ||
| + | ^Conclusion| Acupuncture and moxibustion might be effective for the management of nausea and vomiting in early pregnant women. Moreover, acupuncture might be a relatively safe treatment for pregnancy.| | ||
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| + | === Jin 2024 === | ||
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| + | Jin B, Han Y, Jiang Y, Zhang J, Shen W, Zhang Y. Acupuncture for nausea and vomiting during pregnancy: A systematic review and meta-analysis. Complement Ther Med. 2024 Oct;85:103079. https://doi.org/10.1016/j.ctim.2024.103079 | ||
| + | ^Background and objectives|Pregnant women commonly experience challenging nausea and vomiting, which significantly affect their general well-being and daily life. Although medication is often used for relief, it may not alleviate symptoms completely, emphasizing the need for complementary therapies. Acupuncture is one of the complementary treatments for nausea and vomiting of pregnancy (NVP). Studying the outcomes of acupuncture for NVP can shed light on this issue and inform treatment guidelines. Therefore, we systematically evaluated the effectiveness and safety of acupuncture in managing NVP, considering the traditional meridian and acupoint theories.| | ||
| + | ^Methods| PubMed, Embase, Web of Science, Cochrane Central Register of Controlled Trials, China National Knowledge Infrastructure, Wanfang Database, Chinese Science and Technology Periodical Database, ClinicalTrials.gov, and the Chinese Clinical Trial Registry were searched on May 1, 2024. Randomized controlled trials (RCTs) that compared acupuncture for NVP with sham acupuncture, placebo, and Western medicine (WM) or acupuncture plus WM with WM alone were included. The risk of bias was assessed using the Cochrane risk-of-bias tool. A meta-analysis was conducted using RevMan 5.4.1, and the quality of evidence for each outcome was evaluated using the Grading of Recommendations, Assessment, Development, and Evaluation approach.| | ||
| + | ^Results| **Twenty-four RCTs** (with 26 publications) involving **2390 women** were included. Acupuncture plus WM significantly led to a reduction in Pregnancy-Unique Quantification of Emesis (PUQE) scores and ineffective rates compared with WM alone (PUQE: mean difference [MD] -1.95, 95 % confidence interval [CI] -3.08 to -0.81, P = 0.0008, I2 = 90 %, six studies; ineffective rates: risk ratio [RR] 0.27, 95 % CI 0.19 to 0.39, P < 0.00001, I2 = 7 %, 16 studies). It also resulted in a greater improvement in ketonuria, shorter length of stay, and lower scores on the NVP Quality of Life and Chinese Medicine Syndrome Scale. Acupuncture was superior to WM in terms of reduction in ineffective rates (RR 0.50, 95 % CI 0.30 to 0.81, P = 0.006, I2 = 0 %, five studies). Acupuncture and WM had comparable results in improvement in PUQE scores (MD -0.80, 95 % CI -3.06 to 1.46, P = 0.49, I2 = 89 %, three studies) and ketonuria negative rates. The evidence is not clear regarding the impact of acupuncture on depression and anxiety compared with that of sham acupuncture. The incidence of severe adverse events was not significantly different between acupuncture and WM or sham acupuncture. Evidence certainty ranged from moderate to very low. Of the 24 RCTs, 19 used the Neiguan (PC6) acupoint, 16 used the Zusanli (ST36) acupoint, and 13 used the Zhongwan (CV12) acupoint.| | ||
| + | ^Conclusion| According to the current systematic review and meta-analysis, acupuncture combined with WM may be a more effective treatment for NVP than WM alone. Furthermore, acupuncture may be as effective as WM. PC6, ST36, and CV12 are the most commonly used acupoints. Although more robust and larger studies are required, the current evidence supports the use of acupuncture in NVP treatment, as it has been demonstrated to be safe.| | ||
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| + | === Tan 2023 ☆ === | ||
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| + | Tan MY, Shu SH, Liu RL, Zhao Q. The efficacy and safety of complementary and alternative medicine in the treatment of nausea and vomiting during pregnancy: A systematic review and meta-analysis. Front Public Health. 2023 Mar 9;11:1108756. https://doi.org/10.3389/fpubh.2023.1108756 | ||
| + | ^Background| Complementary and alternative medicine (CAM) therapies are widely used for nausea and vomiting during pregnancy (NVP) due to the limitations of conventional medicine. However, their efficacy and safety remain controversial. Therefore, this meta-analysis was performed to assess the improvement of CAM therapy on NVP.| | ||
| + | ^Methods| Randomized controlled trials (RCTs) were searched for where the trial group was CAM and the control group was a conventional medicine or a placebo for NVP. This was done via 8 databases, including PubMed, EMBASE, the Cochrane Library, Web of Science, China National Knowledge Infrastructure, Wanfang, SinoMed, and VIP, from inception to October 25, 2022. The Grades of Recommendation, Assessment, Development and Evaluation (GRADE) was used to assess the quality of evidence. The Stata 15.0 software was used to perform the meta-analysis.| | ||
| + | ^Results|Thirty-three RCTs were included in this study. **The acupuncture** treatment was superior to conventional medicine at the effective rate [RR = 1.71, 95% CI (1.02, 2.86), P = 0.042; Low-quality evidence]. Ginger had more significant effects than conventional medicine at the Rhodes index [WMD = -0.52, 95% CI (-0.79, -0.24), P ≤ 0.001; Moderate-quality evidence] and it had the same effect as drugs to relieve vomiting [SMD = 0.30, 95% CI (-0.12, 0.73), P = 0.160; Low-quality evidence]. Compared with placebo, ginger had a higher effective rate [RR = 1.68, 95% CI (1.09, 2.57), P = 0.018; Low-quality evidence], and lower Visual analog scale (VAS) of Nausea [WMD = -1.21, 95% CI (-2.34, -0.08), P = 0.036; Low-quality evidence]. Ginger had the same antiemetic effect as placebo [WMD = 0.05, 95% CI (-0.23, 0.32), P = 0.743; Low-quality evidence]. **Acupressure** was superior to conventional medicine at the reduction of antiemetic drugs [SMD = -0.44, 95% CI (-0.77, -0.11), P = 0.008; Low-quality evidence], and at the effective rate [RR = 1.55, 95% CI (1.30, 1.86), P ≤ 0.001; Low-quality evidence]. **Acupressure** had the same effect as placebo at the effective rate [RR = 1.25, 95% CI (0.94, 1.65), P = 0.124; Low-quality evidence]. Overall, CAM therapy was safer than conventional medicine or a placebo.| | ||
| + | ^Conclusion| The results showed that CAM therapies were able to alleviate NVP. However, due to the low quality of existing RCTs, more RCTs with large sample sizes are needed to validate this conclusion in the future.| | ||
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| + | === Nassif 2022 ☆=== | ||
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| + | Nassif MS, Costa ICP, Ribeiro PM, Moura CC, Oliveira PE. Integrative and complementary practices to control nausea and vomiting in pregnant women: a systematic review. Rev Esc Enferm USP. 2022 Oct 21;56:e20210515. English, Portuguese. https://doi.org/10.1590/1980-220X-REEUSP-2021-0515en. | ||
| + | ^Objective| to synthesize the evidence available in the literature on the effects of integrative and complementary practices in nausea and vomiting treatment in pregnant women.| | ||
| + | ^Method| a systematic review, reported according to PRISMA and registered in PROSPERO. The search for studies was carried out in 11 databases. To assess risk of bias in randomized clinical trials, the Cochrane Collaboration Risk of Bias Tool (RoB 2) was used.| | ||
| + | ^Results|the final sample consisted of 31 articles, divided into three categories: aromatherapy, phytotherapy and acupuncture. It was observed that aromatherapy with lemon essential oil, ginger capsules, pericardial 6 point acupressure were the interventions that proved to be effective. Less than half of studies reported adverse effects, with mild and transient symptoms predominating. Most articles were classified as "some concern" in risk of bias assessment.| | ||
| + | ^Conclusion|the three most effective interventions to control gestational nausea and vomiting were aromatherapy, herbal medicine and **acupuncture**, with significant results in the assessment of individual studies.| | ||
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| + | === Lu 2021 ★★=== | ||
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| + | Lu H, Zheng C, Zhong Y, Cheng L, Zhou Y. Effectiveness of Acupuncture in the Treatment of Hyperemesis Gravidarum: A Systematic Review and Meta-Analysis. Evid Based Complement Alternat Med. 2021. [220826]. https://doi.org/10.1155/2021/2731446 | ||
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| + | ^Background| Hyperemesis gravidarum (HG) is a common gastrointestinal disease afflicting gravidas. It usually results in hospital admission in early pregnancy. | | ||
| + | ^Objective| Through a meta-analysis, this study intended to explore acupuncture's clinical efficacy in treating HG. | | ||
| + | ^Materials and methods| A comprehensive search of PubMed, the Cochrane Library, EMBASE, Web of Science, China National Knowledge Infrastructure (CNKI), Chinese Biological Medical (CBM), Wanfang Database, and China Science and Technology Journal (VIP) for published clinical randomized controlled trials (RCTs) of acupuncture for treating HG was conducted from the date of database creation to 20th January 2021. We also searched grey literature in four databases: Chinese Cochrane Center, Chinese Clinical Trial Registry, GreyNet International, and Open Grey from their inception to 20th January 2021. Two authors independently screened the literature, extracted data, and evaluated the quality of the literature with Cochrane Handbook 5.1.0 and Review Manager 5.2 software. Review Manager 5.2 and STATA 12.0 software were applied to analyze data. Heterogeneity analysis was performed by the Cochran Chi-square test and I 2 statistic. Egger's tests together with funnel plots were used to identify publication bias. | | ||
| + | ^Results| A total of **16 trials covering 1043 gravidas** were included. Compared with the conventional treatment, acupuncture had a significantly higher effective rate (OR: 8.11, 95% CI: 5.29∼12.43; P < 0.00001), a higher conversion rate of urine ketone (RR: 1.36, 95% CI: 1.15∼1.60; P=0.0003), an improvement rate of nausea and vomiting (OR: 26.44, 95% CI: 3.54∼197.31; P=0.001), and a relatively higher improvement rate of food intake (RR: 1.17, 95% CI: 1.01∼1.36; P=0.04). Acupuncture also shortened hospitalization time and manifested with a lower pregnancy termination rate and fewer adverse events. Nevertheless, no statistical variation in the improvement of nausea intensity, vomiting episodes, and lassitude symptom, recurrence rate, and serum potassium was observed. | | ||
| + | ^Conclusion| Our study suggested that acupuncture was effective in treating HG. However, as the potential inferior quality and underlying publication bias were found in the included studies, there is a need for more superior-quality RCTs to examine their effectiveness and safety.| | ||
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| + | === Sridharan 2020 ☆ === | ||
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| + | Sridharan K, Sivaramakrishnan G. Interventions for treating hyperemesis gravidarum: a network meta-analysis of randomized clinical trials. J Matern Fetal Neonatal Med. 2020;33(8):1405-1411. {{:medias securises:acupuncture:evaluation:gyneco-obstetrique:sridharan-216323.pdf|[216323]}}. [[https://doi.org/10.1080/14767058.2018.1519540|doi]] | ||
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| + | ^Background|Several interventions were explored in clinical trials for treating hyperemesis gravidarum (HG). The present study is a network meta-analysis of such interventions. | | ||
| + | ^Methods|Electronic databases were searched for appropriate randomized clinical trials comparing interventions for treatment of patients with HG. Control of HG symptoms was the primary outcome and emetic episodes, hospital stay, nausea scores, patients requiring rescue antiemetics, hospital readmission, adverse events, and adverse pregnancy outcomes were the secondary outcome measures. Random-effects model was used and odds ratio (OR) [95% confidence interval (CI)] was the effect estimate for categorical outcomes and weighted mean difference (WMD) [95% confidence interval] for numerical outcomes. | | ||
| + | ^Results|**Twenty studies were included** in the systematic review and 18 in the meta-analysis. Acupuncture (OR: 18.9; 95% CI: 2.1, 168), acupressure (OR: 26.7; 95% CI: 2.5, 283.1) and methylprednisolone (OR: 6.7; 95% CI: 1.1, 38.8) were associated with better control of HG symptoms than standard of care. Acupressure decreases the requirement of rescue antiemetics (OR: 0.06; 95% CI: 0.01, 0.44); ondansetron with reduced hospital stay (WMD: -0.2; 95% CI: -0.31, -0.01) and diazepam with reduced risk of hospital admission (OR: 0.11; 95% CI: 0.01, 0.95). The quality of evidence is very low. | | ||
| + | ^Conclusion| Acupuncture, acupressure, and methylprednisolone were observed with better therapeutic benefits than other interventions for treating HG. However, the pooled estimates may change with the advent of results from future head-to-head clinical trials. | | ||
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| - | === Sridharan 2018 Ø === | + | === Sridharan 2018 ☆ === |
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| ==== Special Acupuncture Techniques ==== | ==== Special Acupuncture Techniques ==== | ||
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| + | === Comparison of Acupuncture techniques === | ||
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| + | == Liu 2025 == | ||
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| + | Liu H, Liao C, Deng J, Yang Y, Yang Y, Guo X, Liu C, Tang C. Efficacy of acupoint-related therapies for nausea and vomiting in pregnancy: a Bayesian network meta-analysis. Front Med (Lausanne). 2025 Sep 30;12:1589950. https://doi.org/10.3389/fmed.2025.1589950 | ||
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| + | ^Objective|Bayesian network meta-analysis was used to compare the efficacy of different acupoint-related treatments for Nausea and Vomiting of Pregnancy (NVP).| | ||
| + | ^Methods|PubMed, Embase, Cochrane Library, CNKI, Wan Fang, and VIP databases were systematically searched from the time of library construction to February 20, 2025, to include randomized controlled trials (RCTs) comparing acupoint-related treatments for the treatment of nausea and vomiting in pregnancy. Literature screening, data extraction and risk of bias assessment were performed independently by two investigators, Bayesian network Meta-analysis was performed by R4.4.1 software.| | ||
| + | ^Result|A total of **38 studies containing 1,164 patients** were included, this Bayesian network meta-analysis assessed the efficacy of various treatments for NVP across multiple outcomes. Results indicated that Acupoint Application (AA), Acupressure, Auriculotherapy Acupoint Application (ATAA), Ginger Moxibustion Acupoint Application (GMAA), and Moxibustion Acupoint Application (Mox_AA) were significantly more effective than Press Needle (PN) in improving PUQE scores. Thunder Fire Moxibustion (TFM) ranked highest in efficacy (89.1%), followed by GMAA (74.2%) and Acupressure (70.3%). Regarding overall efficacy, AA was less effective than AA_WA (OR = 0.22) and Acupuncture (OR = 0.44), but more effective than usual care (UT) (OR = 3.76), with AA_WA ranking highest (84.7%). In terms of NVP quality of life, TCM_acupuncture showed the greatest benefit (MD = 30.43), significantly outperforming AA (MD = -42.54), Mox_AA, and UT. Overall, TCM_acupuncture emerged as the most effective treatment for both symptom relief and quality of life improvement, followed by Mox_AA and ATAA, while UT was the least effective across all measures.| | ||
| + | ^Conclusion|Overall, the analyses showed that TFM may be the most effective in treating NVP, followed by GMAA and ear pressure therapy. Compared to PN, AA, auricular pressure therapy, ATAA and GMAA were more effective. AA was more effective than UT, but not as effective as AA_WA and acupuncture. In terms of quality-of-life improvement, TCM_acupuncture may be the most effective, followed by Mox_AA and ATAA, and UT was the least effective. Overall, acupuncture-based treatments, especially Thunder Fire Moxibustion and TCM acupuncture, performed better in the treatment of NVP.| | ||
| + | === Acupressure === | ||
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| + | == Gong 2024 == | ||
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| + | Gong J, Gu D, Wang H, Zhang F, Shen W, Yan H, Xie J. Effect of acupressure in nausea and vomiting treatment during pregnancy: A meta-analysis. Explore (NY). 2024 Jan-Feb;20(1):17-26. https://doi.org/10.1016/j.explore.2023.06.015 | ||
| + | ^Background and objective| Many women experience nausea and vomiting in early pregnancy. Regardless of the disease severity, it affects the work and life of pregnant women. However, drug treatment may potentially impact the foetus; thus, alternative safe and effective measures are essential. We aimed to evaluate the effect of acupressure, a non-drug treatment for nausea and vomiting, during pregnancy.| | ||
| + | ^Methods| PubMed, EMBASE, Cochrane, Web of Science, CNKI, CBM, VIP, and Wanfang databases were searched using 'pregnancy', 'nausea', 'vomiting', and 'acupressure' as keywords. The search period was from database inception to 30 November 2022. Two researchers independently screened articles, extracted data, and used RevMan 5.4 software for statistical analysis.| | ||
| + | ^Results| We included **33 trials and 3 390 patients** in this meta-analysis. Acupressure was effective for women with nausea and vomiting during pregnancy (odds ratio (OR)= 4.81, 95% confidence interval (CI) [3.47, 6.68]; p<0.0001); it significantly reduced the nausea score of the Rhodes index (mean square deviation (MD): -3.21, 95% CI [-4.85, -1.57], Z = 3.83, p = 0.0001), modified Pregnancy Unique Quantification of Emesis and Nausea score (MD: -2.18, 95% CI [-3.21, -1.15], Z = 4.15, p<0.0001), and hospital stay (OR=-3.27, 95% CI [-6.18, -0.36]; p = 0.03) and improved quality of life (MD: -14.06,95% CI [- 17.31, -10.18], Z = 8.48, p<0.00001). However, no significant difference was observed in nursing satisfaction and anxiety scores (OR=4.13, 95% CI [0.89, 19.15]; p = 0.07) (MD: -13.26,95% CI [-32.04,5.53], Z = 1.38, p = 0.17).| | ||
| + | ^Conclusions| This meta-analysis provides evidence of a non-drug intervention for women with nausea and vomiting during pregnancy; acupressure effectively reduces nausea and vomiting during pregnancy.| | ||
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| ^Results|A total of 10 articles met the inclusion criteria, including 834 patients with 417 cases in the treatment group and 417 cases in the control group. The meta - analysis showed that the cure rate, the effective rate and the ameliorative situation of urine ketone of acupoint injection were better than those of intravenous infusion in the treatment of hyperemesis gravidarum. In terms of the cure rate, OR =4. 18,95% CI(3. 02, 5.78), P <0.00001. In terms of the effective rate, OR= 4.95 ,95% CI(2. 66, 9.23), P <0.000 01. Moreover, with the Egger's test, the publication bias were analyzed. The cure rate was chose to analyze the efficiency of the meta - analysis. | | ^Results|A total of 10 articles met the inclusion criteria, including 834 patients with 417 cases in the treatment group and 417 cases in the control group. The meta - analysis showed that the cure rate, the effective rate and the ameliorative situation of urine ketone of acupoint injection were better than those of intravenous infusion in the treatment of hyperemesis gravidarum. In terms of the cure rate, OR =4. 18,95% CI(3. 02, 5.78), P <0.00001. In terms of the effective rate, OR= 4.95 ,95% CI(2. 66, 9.23), P <0.000 01. Moreover, with the Egger's test, the publication bias were analyzed. The cure rate was chose to analyze the efficiency of the meta - analysis. | | ||
| ^Conclusion|Compared to single intravenous infusion, acupoint injection and acupoint injection plus intravenous infusion can produce a better clinical efficacy with less adverse reactions. | | ^Conclusion|Compared to single intravenous infusion, acupoint injection and acupoint injection plus intravenous infusion can produce a better clinical efficacy with less adverse reactions. | | ||
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| + | ===== Overviews of systematic reviews ===== | ||
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| + | ==== Choi 2025 ==== | ||
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| + | Choi SJ, Choi S, Kim DI. Acupuncture and Herbal Medicine for Nausea and Vomiting in Pregnancy: An Overview and Quality Assessment of Systematic Reviews. Int J Womens Health. 2025 May 11;17:1343-1361. https://doi.org/10.2147/IJWH.S512247 | ||
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| + | ^Backgound|Up to 85% of pregnant women experience nausea and vomiting in pregnancy (NVP), which can impact both the pregnant woman and developing fetus. Traditional East Asian Medicine (TEAM) including acupuncture and herbal medicine has been used to treat NVP; however, its effectiveness remains under debate. This study aimed to systematically review the existing evidence from systematic reviews on the effectiveness of TEAM for NVP and to critically evaluate the quality of these reviews.| | ||
| + | ^Methods|Nine databases were searched from their inception until January 2024. Search terms included, "Hyperemesis gravidarum", "Nausea", "Vomiting", "acupuncture" and "herbal medicine". Systematic reviews (SRs) that evaluated the effect of TEAM treatment for NVP were included. We evaluated methodological quality, reporting quality, and risk of bias using the AMSTAR-2, ROBIS tool, and PRISMA guidelines.| | ||
| + | ^Results|In total, 20,121 publications were retrieved from the databases. **Twenty-five SRs met the inclusion criteria**, indicating that acupuncture and related techniques, and herbal medicines are effective in alleviating NVP. Various methods including traditional acupuncture, acupressure, acupoint injection, electroacupuncture, herbal acupoint patching, and herbal decoctions were used. Herbs like ginger and additional aromatherapies such as lemon and cardamom have also shown beneficial effects. However, there are controversies regarding the consistency of results and the quality of methodologies. Despite low risk of bias across reviews, all were deemed low or critically low in methodological quality, with none fully adhering to PRISMA guidelines.| | ||
| + | ^Conclusion|This comprehensive review underscores the potential of TEAM in managing NVP but highlights significant gaps in research quality and reporting. Future studies of higher methodological quality are essential to validate these findings and guide clinical practice.| | ||
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| | ⊕ positive recommendation (regardless of the level of evidence reported) \\ Ø negative recommendation (or lack of evidence) | | | ⊕ positive recommendation (regardless of the level of evidence reported) \\ Ø negative recommendation (or lack of evidence) | | ||
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| + | ==== Collège national des gynécologues et obstétriciens français (CNGOF, France) 2022 ⊕ ==== | ||
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| + | Deruelle P, Sentilhes L, Ghesquière L, Desbrière R, Ducarme G, Attali L, Jarnoux A, Artzner F, Tranchant A, Schmitz T, Sénat MV. Consensus formalisé d’experts du Collège national des gynécologues et obstétriciens français : prise en charge des nausées et vomissements gravidiques et de l’hyperémèse gravidique [Expert consensus from the College of French Gynecologists and Obstetricians: Management of nausea and vomiting of pregnancy and hyperemesis gravidarum]. Gynecol Obstet Fertil Senol. 2022 Sep 21:S2468-7189(22)00261-6. https://doi.org/10.1016/j.gofs.2022.09.002 | ||
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| + | | Proposition 2.6 – Il est proposé de réserver l’acupression, l’acupuncture et l’électrostimulation aux femmes ayant un score PUQE ≤ 6, si elles devaient être utilisé en sachant que l’amélioration des symptômes après leur prescription n’est pas démontrée.| | ||
| + | ==== National Institute for Health and Care Excellence (NICE) 2021 ⊕ ==== | ||
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| + | NICE guideline NG201 : Antenatal care [R] Management of nausea and vomiting in pregnancy. National Institute for Health and Care Excellence (NICE). 2021. [211646]. | ||
| + | Recommendations: [[https://www.nice.org.uk/guidance/ng201/chapter/Recommendations#routine-antenatal-clinical-care|doi]]. Argument: [[https://www.nice.org.uk/guidance/ng201/evidence/r-management-of-nausea-and-vomiting-in-pregnancy-pdf-331305934365|doi]] | ||
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| + | |// Recommendations//. For pregnant women with moderate‑to‑severe nausea and vomiting: consider intravenous fluids, ideally on an outpatient basis, consider **acupressure** as an adjunct treatment. \\ //Argument//: The committee recommended that **acupressure** should be considered as an adjunct treatment of moderate to severe nausea and vomiting in pregnant women because there was evidence that acupressure in addition to standard care is effective in aiding symptomatic relief during pregnancy, compared to placebo. | | ||
| + | ==== World Health Organization (WHO) 2021 ⊕ ==== | ||
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| + | WHO Guideline on Self-Care Interventions for Health and Well-Being. Geneva: World Health Organization. 2021.186P. [219406]. | ||
| + | [[https://www.who.int/publications/i/item/9789240030909|doi]] | ||
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| + | |Recommendation 3. Interventions for nausea and vomiting Ginger, chamomile, vitamin B6 and/or **acupuncture** are recommended for the relief of nausea in early pregnancy, based on a woman’s preferences and available options. | | ||
| ==== Aetna (insurance provider, USA) 2018 ⊕ ==== | ==== Aetna (insurance provider, USA) 2018 ⊕ ==== | ||
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| |Certains traitements de médecine douce tels que les suppléments de gingembre, l’acupuncture et l’acupression peuvent avoir des effets favorables. (I-A)| | |Certains traitements de médecine douce tels que les suppléments de gingembre, l’acupuncture et l’acupression peuvent avoir des effets favorables. (I-A)| | ||
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| + | ===== Randomized controlled trials ===== | ||
| + | ==== Sources ==== | ||
| + | |||
| + | Systematic reviews and guidelines for a listing of randomized control trials included: | ||
| + | - **Acudoc2**: RCT included in the GERA Database and not cited in other sources. | ||
| + | - **Hu 2024**:Hu Y, Yang Q, Hu X. The efficacy and safety of acupuncture and moxibustion for the management of nausea and vomiting in pregnant women: A systematic review and meta-analysis. Heliyon. 2024 Jan 11;10(2):e24439. https://doi.org/10.1016/j.heliyon.2024.e24439 (n=21) | ||
| + | - **Jin 2024**:Jin B, Han Y, Jiang Y, Zhang J, Shen W, Zhang Y. Acupuncture for nausea and vomiting during pregnancy: A systematic review and meta-analysis. Complement Ther Med. 2024 Oct;85:103079. https://doi.org/10.1016/j.ctim.2024.103079 (n=24) | ||
| + | - **Tan 2023**: Tan MY, Shu SH, Liu RL, Zhao Q. The efficacy and safety of complementary and alternative medicine in the treatment of nausea and vomiting during pregnancy: A systematic review and meta-analysis. Front Public Health. 2023 Mar 9;11:1108756. https://doi.org/10.3389/fpubh.2023.1108756 (n=33) | ||
| + | - **Gong 2021**: Gong J, Gu D, Wang H, Zhang F, Shen W, Yan H, Xie J. Effect of acupressure in nausea and vomiting treatment during pregnancy: A meta-analysis. Explore (NY). 2024 Jan-Feb;20(1):17-26. https://doi.org/10.1016/j.explore.2023.06.015 | ||
| + | - **Lu 2021**: Lu H, Zheng C, Zhong Y, Cheng L, Zhou Y. Effectiveness of Acupuncture in the Treatment of Hyperemesis Gravidarum: A Systematic Review and Meta-Analysis. Evid Based Complement Alternat Med. 2021. [220826]. https://doi.org/10.1155/2021/2731446 | ||
| + | - **Matthews 2015**: Matthews A, Haas DM, O'Mathúna DP, Dowswell T. Interventions for nausea and vomiting in early pregnancy. Cochrane Database Syst Rev. 2015 Sep 8;2015(9):CD007575. https://doi.org/10.1002/14651858.cd007575.pub4 | ||
| + | ==== List ==== | ||
| + | |||
| + | ^ ^ RCT | | control ^ Sources ^ | ||
| + | ^ 2024 | Wang Q, Zhu J. [Clinical study on the treatment of hyperemesis gravidarum by acupuncture based on the theory of regulating the spirit]. Inner Mongolia J Tradit Chin Med. 2024;43(2):102–104. https://doi.org/10.16040/j.cnki.cn15-1101.2024.02.066. | | | Jin 2024, | | ||
| + | ^ 2023 | Lai YQ, Guo QY, Xue D, et al. [Clinical study of acupuncture in the treatment of hyperemesis gravidarum]. Yunnan J Tradit Chin Med Mat Med. 2023;44(2):70–72. https://doi.org/10.16254/j.cnki.53-1120/r.2023.02.023. | | | Jin 2024, | | ||
| + | | | Wu XK, Gao JS, Ma HL, Wang Y, Zhang B, Liu ZL, Li J, Cong J, Qin HC, Yang XM, Wu Q, Chen XY, Lu ZL, Feng YH, Qi X, Wang YX, Yu L, Cui YM, An CM, Zhou LL, Hu YH, Li L, Cao YJ, Yan Y, Liu L, Liu YX, Liu ZS, Painter RC, Ng EHY, Liu JP, Mol BWJ, Wang CC. Acupuncture and Doxylamine-Pyridoxine for Nausea and Vomiting in Pregnancy : A Randomized, Controlled, 2 × 2 Factorial Trial. Ann Intern Med. 2023 Jul;176(7):922-933. https://doi.org/10.7326/m22-2974 | électroacupuncture | sham \\ doxylamine–pyridoxine | Hu 2024, Jin 2024, | | ||
| + | ^ 2022 | Deng L. [Clinical effect of screw acupuncture therapy for spleen-stomach weakened pregnancy obstruction]. China Mod Med. 2022;29(4):134–137. | | | Jin 2024, | | ||
| + | | | Liu L, Hao XY, Cheng YL, et al. [The clinical observation of 212 patients with pregnancy nausea and vomiting treated by acupuncture and medicine]. World J Integr Tradit West Med. 2022;17(2):331–335. https://doi.org/10.13935/j.cnki.sjzx.220225. | | sham | Jin 2024, | | ||
| + | | | Mohd Nafiah NA, Chieng WK, Zainuddin AA, Chew KT, Kalok A, Abu MA, Ng BK, Mohamed Ismail NA, Nur Azurah AG. Effect of Acupressure at P6 on Nausea and Vomiting in Women with Hyperemesis Gravidarum: A Randomized Controlled Trial. Int J Environ Res Public Health. 2022 Sep 1;19(17):10886. https://doi.org/10.3390/ijerph191710886 | acupression 6MC | metoclopramide | Tang 2023 | | ||
| + | | | Zhang CH. [Application of wrist and ankle acupuncture in hyperemesis gravidarum]. Elecrron J Pr Gynecol Endocrinol. 2022;9(29):35–37. https://doi.org/10.3969/j.issn.2095-8803.2022.29.011. | | | Jin 2024, | | ||
| + | ^ 2021 | Chen Y, Hu S, Ning Y, Liao J, Yu D. [The effect of huolong moxibustion for treatment of hyperemesis gravidarum with spleen and stomach weakness]. Chin Acupunct Moxibustion. 2021;41(4):449–450. | | | Hu 2024, | | ||
| + | | | Lyu J, Wang R, Wang Q. [Efficacy of needling eight confluence points combined with press-needle embedding in treating pernicious vomiting due to deficiency of spleen and stomach and its influence to the scores of SAS and SDS]. Journal of Clinical Acupuncture and Moxibustion. 2021;37(2):32–35. | | | Hu 2024, | | ||
| + | | | Zhao YT. [Observation of the effect of press-acupuncture therapy on the patients with pregnancy obstruction due to spleen and stomach weakness]. Heilongjiang Univ Chin Med. 2021. | | | Jin 2024, | | ||
| + | ^ 2020 | Ma WJ, Cui SY, Ning Y, et al. [Observation on the therapeutic effect of lingnan flying needling combined with symptomatic supportive therapy in the treatment of hyperemesis gravidarum]. Guangming J Chin Med. 2020;35(2):228–230. https://doi.org/10.3969/j.issn.1003-8914.2020.02.032. | | | Jin 2024, Lu 2021 | | ||
| + | | | Negarandeh R, Eghbali M, Janani L, Dastaran F, Saatchi K. Auriculotherapy as a means of managing nausea and vomiting in pregnancy: a double-blind randomized controlled clinical trial. Complement Ther Clin Pract. 2020;40:101177. | acupuncture auriculaire | sham | | | ||
| + | | | Tara F, Bahrami-Taghanaki H, Amini Ghalandarabad M, Zand-Kargar Z, Azizi H, Esmaily H, Azizi H. The Effect of Acupressure on the Severity of Nausea, Vomiting, and Retching in Pregnant Women: A Randomized Controlled Trial. Complement Med Res. 2020;27(4):252-259. https://doi.org/10.1159/000505637 | acupression 6MC | sham \\ vit B6 + metaclopramide | Tang 2023 | | ||
| + | | | Yan GH. [The clinical observation on the therapeutic effect of wrist-ankle acupuncture on hyperemesis gravidarum]. Fujian University of Traditional Chinese Medicine. 2020. | | | Hu 2024, Jin 2024, | | ||
| + | | | Zhu YR, Fang SF. [Effect of percutaneous electrical stimulation at Neiguan acupoint on hyperemesis gravidarum]. China Modern Doctor. 2020;58:59–61. | électroacupuncture 6MC | injection placebo | Tang 2023 | | ||
| + | ^ 2019 | Yang R. Analysis of the efficacy and safety of acupuncture in the auxiliary treatment of hyperemesis gravidarum. Health Horizon. 2019;7:92. | | | Lu 2021 | | ||
| + | ^ 2018 | Huang Shi-wei. [Therapeutic Observation of the Treatment of Hyperemesis Gravidarum Majorly with Intradermal Needle plus Acupressure]. Shanghai Journal of Acupuncture and Moxibustion. 2018;37(1):51-55. [100905]. | Acupuncture intradermique | | | | ||
| + | | | Qiu Y 25 | Acupression 6MC + 5TR | | Gong 2021 | | ||
| + | | | Yu Xiao-Lei, Liu Jing, Mao Qun-Yan. [Therapeutic Observation of Acupoint injection at Different Groups of Acupoints for Hyperemesis Gravidarum]. Shanghai Journal of Acupuncture and Moxibustion. 2018;37(8):887. [189731]. | Injection au point d'acupuncture | | Acudoc2 | | ||
| + | | | Zhang Wan-Yu, Ding Ying, Jin Yong, Cal Shao-Ren. [Clinical Observation of Acupuncture at the Eight Confluent Points plus Acupoint Sticking for Hyperemesis Gravidarum]. Shanghai Journal of Acupuncture and Moxibustion. 2018;37(8):891. [189499]. | | | Lu 2021 | | ||
| + | ^ 2017 | Adlan AS, Chooi KY, Mat Adenan NA. Acupressure as adjuvant treatment for the inpatient management of nausea and vomiting in early pregnancy: a double-blind randomized controlled trial. J Obstet Gynaecol Res. 2017;43:662–8 | acupression 6MC | sham | Tang 2023 | | ||
| + | | | Shang G, Liu J, Qi B, Liu J, Li H. [Effect observation of modified sini san combined with acupuncture for pregnant vomiting patients with the pattern of liver-stomach disharmony]. Information on Traditional Chinese Medicine. 2017;34(4):113–115. | | | Hu 2024, | | ||
| + | | | Zhong Q. Clinical observation of acupuncture and moxibustion in the treatment of hyperemesis gravidarum. Inner Mongolia Journal of Traditional Chinese Medicine. 2017;36(14):120–1. | | | Lu 2021 | | ||
| + | ^ 2015 | Chong Zeng | acupression 36E + 6MC | | Gong 2021 | | ||
| + | | | Jin Cao | acupression 12VC+6MC+4Rte | | Gong 2021 | | ||
| + | | | Shao G | acupression auriculaire | | Gong 2021 | | ||
| + | | | Xu Y, Huang WZ, Li QW, et al. Clinical observation of acupuncture combined with moxibustion in the treatment of hyperemesis gravidarum with spleen and stomach weakness syndrome type. Journal of Frontiers of Medicine. 2015;5(10):341–2. | | | Lu 2021 | | ||
| + | | | Xueying Wu | acupression 6MC +36E | | Gong 2021 | | ||
| + | | | Yazhen Zeng | acupression 20V +21V | | Gong 2021 | | ||
| + | | | Zhaoqian Zhu | acupression 36E + 6MC | | Gong 2021 | | ||
| + | ^ 2014 | Jin LH, Hu DX. Clinical observation on filiform needling combined with symptomatic and supportive therapy for 20 cases of intractable hyperemesis gravidarum. J Tradit Chin Med. 2014;55(11):939–941. https://doi.org/10.13288/j.11-2166/r.2014.11.011. | | | Hu 2024, Jin 2024, Lu 2021 | | ||
| + | | | Saberi F, Sadat Z, Abedzadeh-Kalahroudi M, Taebi M. Effect of ginger on relieving nausea and vomiting in pregnancy: a randomized, placebo-controlled trial. Nurs Midwifery Stud. 2014 Apr;3(1):e11841. doi: 10.17795/nmsjournal11841. Epub 2014 Apr 17. https://doi.org/10.17795/nmsjournal11841 | acupression 6MC | gingembre | Matthews 2015 | | ||
| + | ^ 2013 | Agham | acupression 6MC | sham | Gong 2021 | | ||
| + | | | Jin Ruifen | acupression 36E + 6MC | | Gong 2021 | | ||
| + | | | Ma JZ, Meng LP. [Observations on the therapeutic effect of applying the method of matching acupoints to treat 30 cases of hyperemesis gravidarum]. J Sichuan Tradit Chin Med. 2013;31(11):134–135. | | | Hu 2024, Jin 2024, Lu 2021 | | ||
| + | | | Sabeiri | | | Gong 2021 | | ||
| + | | | Xie H. [Therapeutic observation on acupuncture for hyperemesis gravidarum]. Shanghai Journal of Acupuncture and Moxibustion. 2013;32(9):734–735. | | | Hu 2024, Tang 2023 | | ||
| + | | | Ye Chunmei | Acupression shenmen auriculaire | | Gong 2021 | | ||
| + | | | Zhang X. [Therapeutic effect of acupuncture combined with psychological counseling in treating 31 cases of hyperemesis gravidarum]. Hunan J Tradit Chin Med. 2013;29(6):74–75. https://doi.org/10.16808/j.cnki.issn1003-7705.2013.06.040. | | | Jin 2024, Lu 2021 | | ||
| + | ^ 2012 | Lu X. [The effect of citicoline combined with moxibustion in the treatment of hyperemesis gravidarum]. Zhejiang JITCWM. 2012;22(10):806–807. | | | Hu 2024, | | ||
| + | | | Naeimi Rad M, Lamyian M, Heshmat R, Jaafarabadi MA, Yazdani S. A randomized clinical trial of the efficacy of KID21 point (Youmen) acupressure on nausea and vomiting of pregnancy. Iran Red Crescent Med J. 2012;14:697–701. | acupression 21Rn | sham | Tang 2023, Gong 2021 | | ||
| + | | | Yan L, Liu RR, Ji FS, et al. [Observations on the efficacy of acupuncture therapy in the treatment of hyperemesis gravidarum]. Mod J Integr Tradit Chin West Med. 2012;21(29):3246–3304. | | | Jin 2024, Lu 2021 | | ||
| + | | | Zhou Y. [Gastric Tocolysis Soup Combined with Acupuncture Therapy Hyperemesis Gravidarum Incoordination between the Liver and Stomach Syndrome Clinical Observation] [Master’s Degree]. Hunan University of Chinese Medicine; 2012. | | | Hu 2024, | | ||
| + | ^ 2010 | Khavandizadeh AS, Mahfouzi B. Evaluation of the effects of acupressure by sea band on nausea and vomiting in pregnancy. Iranian Journal of Obstetrics, Gynecology and Infertility. 2010;13(2):39-44. | acupression 6MC | sham | Matthews 2015 | | ||
| + | | | Liang SD, Huang Y. [Observation on the efficacy of plum blossom needle in treating 24 cases of severe vomiting in pregnancy by percussing the frontal and temporal regions through the meridians]. Chin Fore Med Res. 2010;8(8):90–91. | | | Jin 2024, | | ||
| + | | | Sinha A, Paech MJ, Thew ME, Rhodes M, Luscombe K, Nathan E, et al. A randomised, double-blinded, placebo-controlled study of acupressure wristbands for the prevention of nausea and vomiting during labour and delivery. Int J Obstet Anesth. 2011;20:110–7. | | | Tang 2023 | | ||
| + | ^ 2009 | Mao ZN, Liang CE. [Observation on therapeutic effect of acupuncture on hyperemesis gravidarum]. Chinese Acupuncture and Moxibustion. 2009;29(12):973–6. [154621]. \\ Zhong Nan, Mao, and Chuta E, Liang. Observation on the therapeutic effects of acupuncture on hyperemesis gravidarum. International Journal of Clinical Acupuncture. 2010;2:60–65. [162879]. | | | Hu 2024, Jin 2024, Lu 2021 | | ||
| + | | | Xu Y. [The effect of moxibustion for treatment of hyperemesis gravidarum]. Today Nurse. 2009;(9):66–67. | | | Hu 2024, | | ||
| + | | | Zhang H, Gu L. [Clinical observation on therapeutic effect of acupuncture and moxibustion and acupoint injection on hyperemesis gravidarum to search for a more effective method for treatment of hyperemesis gravidarum]. China Practical Medical. 2009;4(5):46–48. | | | Hu 2024, | | ||
| + | ^ 2008 | Can Gürkan O, Arslan H. Effect of acupressure on nausea and vomiting during pregnancy. Complement Ther Clin Pract. 2008 Feb;14(1):46-52. https://doi.org/10.1016/j.ctcp.2007.07.002 | | | Acudoc2 | | ||
| + | | | Chen J, Ning WX. Transcutaneous electro acupuncture stimulation in treatment of 18 cases of hyperemesis gravidarum. Chin J Tradit Med Sci Technol. 2008;15:231–2. | | | Tang 2023 | | ||
| + | | | Puangsricharern A, Mahasukhon S. Effectiveness of auricular acupressure in the treatment of nausea and vomiting in early pregnancy. J Med Assoc Thai. 2008;91(11):1633-8. https://thaiscience.info/Journals/Article/JMAT/10402675.pdf | acupression auriculaire | | Tang 2023, Gong 2021 | | ||
| + | | | Su QL, Wang HY, Zhao WJ. [Clinical observation on the treatment of 18 cases of hyperemesis gravidarum by combining acupressure of head and face with acupuncture of Neiguan]. Jiangsu J Tradit Chin Med. 2008;40(4):55–56. | | | Jin 2024, | | ||
| + | | | Sun JH. Observation on therapeutic effect of acupoint injection on hyperemesis gravidarum. Chin J Misdiag. (2009) 9:2846–7. | | | Tang 2023 | | ||
| + | | | Wang RY. [Clinical observation on the treatment of hyperemesis gravidarum by acupuncture with acupoint method]. Shanxi Med J. 2008;37(2):135–136. | | | Hu 2024, Jin 2024, Lu 2021 | | ||
| + | ^ 2007 | Jamigorn M, Phupong V. Acupressure and vitamin B6 to relieve nausea and vomiting in pregnancy: a randomized study. Arch Gynecol Obstet. 2007 Sep;276(3):245-9. doi: 10.1007/s00404-007-0336-2. Epub 2007 Feb 21. https://doi.org/10.1007/s00404-007-0336-2 | acupression 6MC | Vit B6 | Tang 2023, Matthews 2015 | | ||
| + | | | Liu S. [Clinical study on TCM and acupuncture combined treating hyperemesis gravidarum]. Journal of Liaoning University of TCM. 2007;(6):145–146. | | | Hu 2024, | | ||
| + | | | Wang MZ, Li XB, Huang LY, et al. [Effect of along-channel plum blossom percussion used in treating psychological problems caused by severe pregnant vomit]. Mod Nurs. 2007;13(31):2976–2977. | | | | | ||
| + | ^ 2006 | Heazell A, Thorneycroft J, Walton V, Etherington I. Acupressure for the in-patient treatment of nausea and vomiting in early pregnancy: a randomized control trial. Am J Obstet Gynecol. 2006 Mar;194(3):815-20. https://doi.org/10.1016/j.ajog.2005.08.04216522418. | acupression 6MC | sham | Tang 2023 | | ||
| + | | | Shin HS, Song YA. [The effect of P6 acupressure for symptom control in pregnant women having hyperemesis gravidarum]. Taehan Kanho Hakhoe Chi. 2005 Jun;35(3):593-601. https://doi.org/10.4040/jkan.2005.35.3.593 \\ Shin HS, Song YA, Seo S. Effect of Nei-Guan point (P6) acupressure on ketonuria levels, nausea and vomiting in women with hyperemesis gravidarum. J Adv Nurs. 2007 Sep;59(5):510-9.https://doi.org/10.1111/j.1365-2648.2007.04342.x | acupression 6MC | sham | Acudoc2 | | ||
| + | | | Xie HY. Clinical Effects of the Combination of Acupuncture and Medicine on the Ketone Bodies in Hyperemesis Gravidarum. Nanjing University of Chinese Medicine,; 2007. | | | Jin 2024, Lu 2021 | | ||
| + | ^ 2005 | Neri I, Allais G, Schiapparelli P, Blasi I, Benedetto C, Facchinetti F. Acupuncture versus pharmacological approach to reduce Hyperemesis gravidarum discomfort. Minerva Ginecol. 2005 Aug;57(4):471-5. PMID: 16170293. | | | Acudoc2 | | ||
| + | | | Zhang HH. [Observation on therapeutic effect of acupuncture and moxibustion on hyperemesis gravidarum]. Chinese Acupuncture and Moxibustion. 2005;25(7):469–70. [120476]. | | | Hu 2024, Lu 2021 | | ||
| + | ^ 2004 | Habek D, Barbir A, Habek JC, Janculiak D, Bobić-Vuković M. Success of acupuncture and acupressure of the Pc 6 acupoint in the treatment of hyperemesis gravidarum. Forsch Komplementarmed Klass Naturheilkd. 2004 Feb;11(1):20-3. https://doi.org/10.1159/000077192 | acupuncture 6MC \\ acupression 6MC | sham | Hu 2024, Jin 2024, Tang 2023, Lu 2021 | | ||
| + | ^ 2003 | Rosen T, de Veciana M, Miller HS, Stewart L, Rebarber A, Slotnick RN. A randomized controlled trial of nerve stimulation for relief of nausea and vomiting in pregnancy. Obstet Gynecol. 2003 Jul;102(1):129-35. https://doi.org/10.1016/s0029-7844(03)00375-2 | électrostimulation 6MC | sham | Matthews 2015 | | ||
| + | ^ 2002 | Smith C, Crowther C, Beilby J. Acupuncture to treat nausea and vomiting in early pregnancy: a randomized controlled trial. Birth. 2002 Mar;29(1):1-9. https://doi.org/10.1046/j.1523-536x.2002.00149.x | acupuncture \\ acupression 6MC | sham | Hu 2024, Jin 2024, Tang 2023, Matthews 2015 | | ||
| + | ^ 2001 | Knight B, Mudge C, Openshaw S, White A, Hart A. Effect of acupuncture on nausea of pregnancy: a randomized, controlled trial. Obstet Gynecol. 2001 Feb;97(2):184-8. doi: 10.1016/s0029-7844(00)01152-2. https://doi.org/10.1016/s0029-7844(00)01152-2 | acupuncture | sham | Hu 2024, Jin 2024, Tang 2023, Matthews 2015 | | ||
| + | | | Norheim AJ, Pedersen EJ, Fønnebø V, Berge L. Acupressure treatment of morning sickness in pregnancy. A randomised, double-blind, placebo-controlled study. Scand J Prim Health Care. 2001 Mar;19(1):43-7. https://doi.org/10.1080/028134301300034666 | acupression 6MC | sham | Matthews 2015 | | ||
| + | | | Steele NM, French J, Gatherer-Boyles J, Newman S, Leclaire S. Effect of acupressure by Sea-Bands on nausea and vomiting of pregnancy. J Obstet Gynecol Neonatal Nurs. 2001 Jan-Feb;30(1):61-70.https://www.jognn.org/article/S0884-2175(15)33873-9/fulltext | | | Acudoc2 | | ||
| + | | | Werntoft E, Dykes AK. Effect of acupressure on nausea and vomiting during pregnancy. A randomized, placebo-controlled, pilot study. J Reprod Med. 2001 Sep;46(9):835-9. https://pubmed.ncbi.nlm.nih.gov/11584487/ | acupression 6MC | sham | Matthews 2015 | | ||
| + | ^ 2000 | Carlsson CP, Axemo P, Bodin A, Carstensen H, Ehrenroth B, Madegård-Lind I, Navander C. Manual acupuncture reduces hyperemesis gravidarum: a placebo-controlled, randomized, single-blind, crossover study. J Pain Symptom Manage. 2000 Oct;20(4):273-9. https://doi.org/10.1016/s0885-3924(00)00185-8 | acupuncture 6MC | sham | Tang 2023 | | ||
| + | ^ 1996 | O'Brien B, Relyea MJ, Taerum T. Efficacy of P6 acupressure in the treatment of nausea and vomiting during pregnancy. Am J Obstet Gynecol. 1996 Feb;174(2):708-15. doi: 10.1016/s0002-9378(96)70454-4. https://doi.org/10.1016/s0002-9378(96)70454-4 | acupression 6MC | sham | Matthews 2015 | | ||
| + | ^ 1995 | Fan YJ. Observation on the therapeutic effect of moxibustion for treatment of pregnant vomiting. World Journal of Acupuncture-Moxibustion. 1995;5(4):31–3. [85158]. | | | Acudoc2 | | ||
| + | | | Sun YH, Cui L. [The role of acupuncture in the treatment of hyperemesis gravidarum]. J Jiangsu Univ (Med Ed). 1995;5(3):249. https://doi.org/10.13312/j.issn.1671-7783.1995.03.077. | | | Jin 2024, , Lu 2021 | | ||
| + | ^ 1994 | Belluomini J, Litt RC, Lee KA, Katz M. Acupressure for nausea and vomiting of pregnancy: a randomized, blinded study. Obstet Gynecol. 1994 Aug;84(2):245-8. | acupression 6MC | sham | Gong 2021, Matthews 2015 | | ||
| + | ^ 1989 | Hyde E. Acupressure therapy for morning sickness: a controlled clinical trial. J Nurse Midwifery. 1989;34:171–8. | acupression | placebo | Tang 2023 | | ||
| + | | | Root DT. P6 acupressure reduces morning sickness. J R Soc Med. 1989;82:635. | | placebo | Tang 2023 | | ||
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